I work with Prof. Julian Parkhill at the Department of Veterinary Medicine (Pathogen Genetics and Evolution Group) and and Prof. Andres Floto at the Department of Medicine and the LMB (Floto Lab).
I want to know how, when and why bacteria use their genes and their products, and ultimately, what makes a successful pathogen.
To study this, I use microbial functional genomics, to analyse the behaviour of bacterial pathogens, in particular Klebsiella pneumoniae and other Enterobacteriaceae species (Salmonella Typhimurium, Enterobacter cloacae) and others, such as Mycobacterium abscessus or Burkholderia cenocepacia.
My main research interests are Antimicrobial Resistance in Enterobacteriaceae and Host-Pathogen Interactions of Klebsiella pneumoniae. Therefore, I am using different sequencing-based methods (functional genomics) to understand how bacteria adapt to certain stresses (gene regulation) and which genes are important during such conditions (gene fitness).
